Recent Advances in Plant-Based, Traditional, and Natural Medicines

Subramanyam Vemulpad, Joanne Jamie

ISBN: 978-1-771-88013-8
Publisher/Imprint: AAP, CRC Press (Taylor & Francis Group)
Pages: 398
Format: Print/e-Book
Language: English
Edition/Volume: 1st
© Year: 2014
Publication date: March 2014



About the Book

The purpose of this book is to discuss several medicinal plants to find wider application in the domain of medicinal, clinical, and pharmaceutical treatment. Recent Advances in Plant-Based, Traditional, and Natural Medicines serves as a useful source of ideas and an inspiration for further cell and molecular biology research toward developing drugs and treatments from these traditional and plant-based remedies.

The book covers a variety of topics and

  • considers the current state of research of traditional and plant-based medicines

  • covers the current status of ethnomedicine and medicinal plant discovery

  • presents the clinical applications of traditional and plant-based medicines

Table of Contents



Part 1: Relevance of Traditional Knowledge to Biological Testing

Chapter 1. The Relevance of Traditional Knowledge Systems for Ethnopharmacological Research: Theoretical and Methodological Contributions

Victoria Reyes-García

Chapter 2. Antioxidative and in vitro Antiproliferative Activity of Arctium lappa Root Extracts
Fabricia S. Predes, Ana L.T.G Ruiz, João E. Carvalho, Mary A. Foglio, and Heidi Dolder

Chapter 3. Interleukin-6 and Cyclooxygenase-2 Down-regulation by Fatty-Acid Fractions of Ranunculus constantinopolitanus
Sabreen F. Fostok, Rima A. Ezzeddine, Fadia R. Homaidan, Jamal A. Al-Saghir, Ralph G. Salloum, Najat A. Saliba, and Rabih S. Talhouk

Chapter 4. An Extract of the Medicinal Mushroom Agaricus blazei Murill Can Protect Against Allergy
Linda K. Ellertsen and Geir Hetland

Chapter 5. Anti-Oxidative Effects of the Biennial Flower of Panax notoginseng Against H2O2-Induced Cytotoxicity in Cultured PC12 Cells
Roy Chi-Yan Choi, Zhiyong Jiang, Heidi Qun Xie, Anna Wing-Han Cheung, David Tai-Wai Lau, Qiang Fu, Tina Tingxia Dong, Jijun Chen, Zhengtao Wang, and Karl Wah-Keung Tsim

Chapter 6. Cytotoxic Activity of Proteins Isolated from Extracts of Corydalis cava Tubers in Human Cervical Carcinoma HeLa Cells
Robert Nawrot, Maria Wolun-Cholewa, Wojciech Bialas, Danuta Wyrzykowska, Stanislaw Balcerkiewicz, and Anna Gozdzicka-Jozefiak

Chapter 7. Arctigenin from Arctium lappa Inhibits Interleukin-2 and Interferon Gene Expression in Primary Human T Lymphocytes
Wei-Jern Tsai, Chu-Ting Chang, Guei-Jane Wang, Tzong-Huei Lee, Shwu-Fen Chang, Shao-Chun Lu, and Yuh-Chi Kuo

Part 2: Targeting Important Diseases Using Natural Products (TK or non-TK based)

Chapter 8. A New Dawn for the Use of Traditional Chinese Medicine in Cancer Therapy
Harendra S. Parekh, Gang Liu, and Ming Q. Wei

Chapter 9. Anti Cancer Effects of Curcumin: Cycle of Life and Death
Gaurisankar Sa and Tanya Das

Chapter 10. Comparative Study of the Antioxidant and Reactive Oxygen Species Scavenging Properties in the Extracts of the Fruits of Terminalia chebula, Terminalia belerica, and Emblica officinalis
Bibhabasu Hazra, Rhitajit Sarkar, Santanu Biswas, and Nripendranath Mandal

Chapter 11. Inhibition of Highly Productive HIV-1 Infection in T cells, Primary Human Macrophages, Microglia, and Astrocytes by Sargassum fusiforme
Elena E. Paskaleva, Xudong Lin, Wen Li, Robin Cotter, Michael T. Klein, Emily Roberge, Er K. Yu, Bruce Clark, Jean-Claude Veille, Yanze Liu, David Y-W Lee, and Mario Canki

Part 3: Molecular Biology, Genomics, and Proteomics: Plant Centered and Person Centered

Chapter 12. The Use of Phylogeny to Interpret Cross-Cultural Patterns in Plant Use and Guide Medicinal Plant Discovery: An Example from Pterocarpus (Leguminosae)
C. Haris Saslis-Lagoudakis, Bente B. Klitgaard, Félix Forest, Louise Francis, Vincent Savolainen, Elizabeth M. Williamson, and Julie A. Hawkins

Chapter 13. Ethnobotany Genomics: Discovery and Innovation in a New Era of Exploratory Research
Steven G. Newmaster and Subramanyam Ragupathy

Chapter 14. Prescriptions of Traditional Chinese Medicine Are Specific to Cancer Types and Adjustable to Temperature Changes
Pei-Hsun Chiu, Hsin-Ying Hsieh, and Sun-Chong Wang

Part 4: Personalized or Person-Centered Medicine

Chapter 15. Traditional, Complementary, and Alternative Medical Systems and Their Contribution to Personalization, Prediction, and Prevention in Medicine: Person-Centered Medicine
Paolo Roberti di Sarsina, Mauro Alivia, and Paola Guadagni


About the Authors/Editors


Subramanyam Vemulpad, PhD
Associate Professor, Department of Chiropractic, Macquarie University Sydney, Australia

Subramanyam Vemulpad, PhD, is a microbiologist, with research and academic experience in India and Malawi prior to migrating to Australia. He joined Sydney’s Macquarie University in 2000 and currently is an Associate Professor in the Department of Chiropractic. He teaches medical microbiology, research methods, and biological effects of radiation. He has many years of experience in demystifying science by conducting hands-on science activities for school children in India. He is the current Chair of the University Biosafety Committee and has served on a variety of university committees, including Biosafety, Ethics (Human Research) and teaching and learning.

Along with co-editor Professor Joanne Jamie, he is co-director of the Indigenous Science Education Program (which won the 2011 Australian Learning and Teaching Council Awards for University Teaching) and the Indigenous Bioresources Research Group at Macquarie University. The group’s major objectives are to systematically document first-hand traditional medicinal plant knowledge of indigenous people using best ethical practices and to apply this knowledge to identify medicinally important compounds following targeted chemical and biological studies.

Professor Vemulpad’s research interests include infectious diseases, plant products as antimicrobial agents, rapid diagnostics, exemplary ethical practices in relation to traditional knowledge ownership, and manual therapy. He has published 75 journal articles and 19 book chapters in these areas.

Joanne Jamie, PhD
Associate Professor, Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia

Joanne Jamie, PhD, was formally trained as a biological/organic chemist at the University of Queensland and at the Australian National University. She entered academia in 1994, following her appointment as Lecturer in biological/medicinal chemistry at the University of Wollongong, NSW, Australia, and has been at Macquarie University, Sydney, Australia, since her appointment in 2000. In her academic positions, Professor Jamie has directed a dynamic research team and conducted teaching in the areas of bioorganic, medicinal, and natural products chemistry. Her current research, based at the Department of Chemistry and Biomolecular Sciences at Macquarie University, includes investigating the structure and function of medically important human enzymes and designing small molecule inhibitors of them for potential therapeutic use; studies on human lens chemistry to understand age-related nuclear cataract, which is a major cause of human blindness; and collaborative research with Indigenous people on traditional knowledge, including investigating medicinal flora, for cultural preservation and drug discovery.

Professor Jamie has published in the areas of isolation, structural elucidation and total synthesis of new human lens (UV) filter compounds and model studies with UV filter compounds and human lens proteins to understand cataract formation; protein expression and purification; identification of proteins with novel function; and design and synthesis of new enzyme inhibitors for therapeutic use.

Professors Jamie and Vemulpad as Co-Directors of the Indigenous Bioresources Research Group work in partnership with Indigenous communities for documentation of traditional knowledge and investigation of biological and chemical properties of medicinal flora.

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